Number of found documents: 3726
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Supercritical water in etching and morphing of siliceous surfaces for analytical separations
Karásek, Pavel; Horká, Marie; Planeta, Josef; Roth, Michal
2018 - English
Applications of supercritical water in etching and morphing of siliceous surfaces for analytical separations are briefly reviewed. Keywords: supercritical water; fused silica capillary; electromigration methods Available in digital repository of the ASCR
Supercritical water in etching and morphing of siliceous surfaces for analytical separations

Applications of supercritical water in etching and morphing of siliceous surfaces for analytical separations are briefly reviewed.

Karásek, Pavel; Horká, Marie; Planeta, Josef; Roth, Michal
Ústav analytické chemie, 2018

Capillary electrophoresis in clinical diagnosis and monitoring
Kubáň, Petr
2018 - English
There is a significant potential of CE to provide a useful analytical tool to analyze noninvasive samples of body fluids and stimulate the cooperation between analytical chemists and clinicians in this interdisciplinary field. Keywords: CE; CE-LIF; clinical diagnosis Available in digital repository of the ASCR
Capillary electrophoresis in clinical diagnosis and monitoring

There is a significant potential of CE to provide a useful analytical tool to analyze noninvasive samples of body fluids and stimulate the cooperation between analytical chemists and clinicians in ...

Kubáň, Petr
Ústav analytické chemie, 2018

UNICELLULAR ALGA CHLORELLA AS A FEED SUPPLEMENT, CURRENT EXPERIENCE AND FUTURE PERSPECTIVES
Kotrbáček, V.; Doucha, Jiří; Kuchařová, V.; Doubek, J.
2017 - English
We studied the effect of Chlorella biomass as a feed supplement. In laying hens we found that diet supplemented with 1 % (i.e. 10 g/kg) of dry disintegrated heterotrophically grown Chlorella biomass significantly increased content of carotenoids in egg yolks of 8 experimental animals already after the first week of supplementation (P<0,01). Compared to 8 control hens these differences remained significantly higher until the end of the eight-week experiment. The average carotenoid concentration was 17,3 mu g per g of yolk in control group and 25,3 mu g per g of yolk in experimental animals (P<0,01). Autotrophically grown Chlorella was supplemented to the 30 gilts one month prior the expected first heat in a dose of 1,5 g per animal per day. These sows entered heat earlier and the number of pregnancy was higher in comparison to the 30 control animals. Other studies observed digestibility of selenium organically bound in Se-enriched Chlorella. The level of selenium in blood, colostrum and also tissues of new born piglets was determined. Group of 8 sows was supplemented with Se-enriched alga during the pregnancy and 3 days after parturition at a dose of 0,3 mg of selenium per 1 kg of feed. The same amount of selenium in the form of sodium selenite was administrated to the control group of 8 individuals. Organic form of selenium significantly increased concentration of Se in blood of sows and colostrum (P<0,05). Piglets born to supplemented sows had also significantly higher level of Se in heart, muscles and liver (P<0.01). The use of fresh Chlorella biomass produced outdoors on a dairy farm was experimentally tested. The liquid fresh biomass applied to dairy cows during the pregnancy at a dose of 15 g dry mass per cow increased the dry matter content in colostrum from 17,5 g per 100 ml of colostrum in control group to 20,5 g per 100 ml of colostrum in supplemented cows (P<0,05). Keywords: Chlorella; feed supplement; flue gas utilization Available at various institutes of the ASCR
UNICELLULAR ALGA CHLORELLA AS A FEED SUPPLEMENT, CURRENT EXPERIENCE AND FUTURE PERSPECTIVES

We studied the effect of Chlorella biomass as a feed supplement. In laying hens we found that diet supplemented with 1 % (i.e. 10 g/kg) of dry disintegrated heterotrophically grown Chlorella biomass ...

Kotrbáček, V.; Doucha, Jiří; Kuchařová, V.; Doubek, J.
Mikrobiologický ústav, 2017

Understanding the Principles of Diastereomeric Complexes of Chiral Urea Derivatives.
Cuřínová, Petra; Jakubec, Martin; Storch, Jan; Holakovský, R.
2017 - English
The main target of this work based on the NMR studies is to elucidate the structural principles which are responsible for the action of the chiral selectors at hand, and thus to be able to predict the new promising structures useful as NMR shift reagents. Keywords: NMR solvating agent; chiral recognition; diastereomeri complex Available in a digital repository NRGL
Understanding the Principles of Diastereomeric Complexes of Chiral Urea Derivatives.

The main target of this work based on the NMR studies is to elucidate the structural principles which are responsible for the action of the chiral selectors at hand, and thus to be able to predict the ...

Cuřínová, Petra; Jakubec, Martin; Storch, Jan; Holakovský, R.
Ústav chemických procesů, 2017

Usage of GP750 Gasifier for Combined Heat and Power Production.
Brynda, J.; Skoblia, S.; Pohořelý, Michael; Beňo, Z.; Moško, Jaroslav
2017 - English
Contribution presents experiences with long-therm operation of GP750 gasifiers in the combined heat and power plant Kozomín. Keywords: gasification; biomass; combined heat and power production Available in a digital repository NRGL
Usage of GP750 Gasifier for Combined Heat and Power Production.

Contribution presents experiences with long-therm operation of GP750 gasifiers in the combined heat and power plant Kozomín.

Brynda, J.; Skoblia, S.; Pohořelý, Michael; Beňo, Z.; Moško, Jaroslav
Ústav chemických procesů, 2017

Changes in Sub-micron Number Size Distributions at Czech Rural and Urban Background Stations in the Last Ten Years.
Zíková, Naděžda; Ondráček, Jakub; Wagner, Zdeněk; Ždímal, Vladimír
2017 - English
In this work, not only total concentrations are evaluated, but also particle number size distributions (PNSD) are compared in the last decade at the two stations, and possible explanations for the change in concentrations and PNSD changes are looked for. Additionally, also the change in the frequency and strength of the NPF events is evaluated.\n Keywords: SMPS; long-term measurement; rural background Available in a digital repository NRGL
Changes in Sub-micron Number Size Distributions at Czech Rural and Urban Background Stations in the Last Ten Years.

In this work, not only total concentrations are evaluated, but also particle number size distributions (PNSD) are compared in the last decade at the two stations, and possible explanations for the ...

Zíková, Naděžda; Ondráček, Jakub; Wagner, Zdeněk; Ždímal, Vladimír
Ústav chemických procesů, 2017

Do Invasive Alien Species Affect Diversity of Local Communities?
Kindlmann, Pavel; Honěk, A.; Martinková, Z.
2017 - English
Here we present results of simulation models to investigate the diversity dynamics in a theoretical system consisting of an "original" community of native species and an invasive alien species that invades this community, thus creating a "new" community. See Kindlmann et al. (2017) for full details of the simulations and results. Keywords: invasive species; local diversity Available at various institutes of the ASCR
Do Invasive Alien Species Affect Diversity of Local Communities?

Here we present results of simulation models to investigate the diversity dynamics in a theoretical system consisting of an "original" community of native species and an invasive alien species that ...

Kindlmann, Pavel; Honěk, A.; Martinková, Z.
Ústav výzkumu globální změny , 2017

Kinetics of Keratin Acidic Hydrolysis in Batch Autoclave.
Hanika, Jiří; Kaštánek, P.; Rousková, Milena; Šabata, Stanislav; Šolcová, Olga
2017 - English
The contribution brings novel data on the non-traditional process presented during previous ICCT 2015 conference1. According to the patent application2 the hydrolysis of waste chicken feathers was performed in a reaction mixture containing water and a soluble acid catalyst with the pKa value lower than 4, in a stirred batch reactor for 0.5 to 10 hours, in the temperature range from 90 to 130°C and at the pertinent vapour pressure of reaction mixture. Kinetics of preparing a mixture of proteins and amino acids by hydrolysis of a waste material containing chicken feathers was investigated in this study.\n Keywords: batch autoclave; reaction micture; experiments Available in a digital repository NRGL
Kinetics of Keratin Acidic Hydrolysis in Batch Autoclave.

The contribution brings novel data on the non-traditional process presented during previous ICCT 2015 conference1. According to the patent application2 the hydrolysis of waste chicken feathers was ...

Hanika, Jiří; Kaštánek, P.; Rousková, Milena; Šabata, Stanislav; Šolcová, Olga
Ústav chemických procesů, 2017

Establishing preclinical proof-of-concept of gene therapy for Huntington disease
Miniariková, J.; Juhás, Štefan; Caron, N.; Spronck, L.; Vallés, A.; De Haan, M.; Blits, B.; Ellederová, Zdeňka; van Deventer, S.; Petry, H.; Southwell, A.; Déglon, N.; Motlík, Jan; Konstantinová, P.; Evers, M.
2017 - English
Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the HTT gene. The translated expanded polyglutamine repeat in the huntingtin protein is known to cause toxic gain-of-function, affecting numerous cellular processes. Our approach involves a new therapeutic modality by developing a single (one-time) treatment for HD based on a gene therapy lowering the expression of the toxic huntingtin using the RNA interference (RNAi) mechanism. Huntingtin lowering is achieved using gene transfer of a cassette encoding an engineered microRNA targeting human HTT, delivered via adeno-associated viral vector serotype 5 (AAV5-miHTT). Keywords: Huntington´s disease Available at various institutes of the ASCR
Establishing preclinical proof-of-concept of gene therapy for Huntington disease

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the HTT gene. The translated expanded polyglutamine repeat in the ...

Miniariková, J.; Juhás, Štefan; Caron, N.; Spronck, L.; Vallés, A.; De Haan, M.; Blits, B.; Ellederová, Zdeňka; van Deventer, S.; Petry, H.; Southwell, A.; Déglon, N.; Motlík, Jan; Konstantinová, P.; Evers, M.
Ústav živočišné fyziologie a genetiky, 2017

Oxidative stress in primary porcine fibroblasts expressing mutated huntingtin
Šmatlíková, Petra; Askeland, G.; Vaškovičová, Michaela; Klíma, Jiří; Motlík, Jan; Eide, L.; Ellederová, Zdeňka
2017 - English
Molecular events, such as protein aggregation, mitochondrial dysfunction, and transcriptional dysregulation have been linked to Huntington’s disease (HD) pathogenesis. Oxidative stress has been considered as one of the key players in disease progression. Though, it is still not clear whether oxidative stress causes HD, or if it is a consequence of other primary events. Keywords: huntingtin Available at various institutes of the ASCR
Oxidative stress in primary porcine fibroblasts expressing mutated huntingtin

Molecular events, such as protein aggregation, mitochondrial dysfunction, and transcriptional dysregulation have been linked to Huntington’s disease (HD) pathogenesis. Oxidative stress has been ...

Šmatlíková, Petra; Askeland, G.; Vaškovičová, Michaela; Klíma, Jiří; Motlík, Jan; Eide, L.; Ellederová, Zdeňka
Ústav živočišné fyziologie a genetiky, 2017

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