Název:
Role FtsH proteas v sinici Synechocystis sp. PCC 6803
Překlad názvu:
Role of FtsH proteases in the cyanobacterium Synechocystis sp. PCC 6803
Autoři:
KRYNICKÁ, Vendula Typ dokumentu: Disertační práce
Rok:
2015
Jazyk:
cze
Abstrakt: [cze][eng] FtsH, proteázy, Synechocystis, membránový protein, kontrola kvality proteinů, PSII, Fur, regulace transkripčních faktorůThis thesis focuses on the functional and structural characterization of FtsH proteases in Synechocystis PCC 6803. One of the aims was to determine localization and subunit organization of FtsH homologues in Synechocystis cells using GST and GFP tagged FtsH derivatives. The main result of the thesis is identification of two FtsH hetero-oligomeric complexes and one homo-oligomeric complex in Synechocystis cells. The large part of the thesis is aimed at establishing the role of the first hetero-oligomeric complex, FtsH2/FtsH3, in quality control of Photosystem II and at identification of a mechanism, how its substrate proteins D1 and D2 are recognized. Another part is dedicated to characterization of the second hetero-oligomeric complex, FtsH1/FtsH3, which consists of two essential FtsH homologues and which is here identified as an important regulatory element in maintaining iron homeostasis.
Klíčová slova:
FtsH; Fur; membrane; photosynthesis; proteases; PSII; quality control; Synechocystis; transcriptional factor regulation; FtsH; Fur; membrane; photosynthesis; proteases; PSII; quality control; Synechocystis; transcriptional factor regulation Citace: KRYNICKÁ, Vendula. Role FtsH proteas v sinici Synechocystis sp. PCC 6803. České Budějovice, 2015. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Instituce: Jihočeská univerzita v Českých Budějovicích
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Plný text je dostupný v digitálním repozitáři JČU. Původní záznam: http://www.jcu.cz/vskp/21885