Strukturní charakteristiky mozku u sexuálních agresorů s diagnózou parafilní poruchy

Bartošová, Martina

Etiology of paraphilic coercive disorder, as well as origin of any paraphilic disorder, remains unresolved. The current approach in research is trying to elucidate the common denominator of paraphilic disorders on the one hand and distinguish their specifics on the other. Findings from neuroscience are increasingly gaining importance in investigating the underlying neurobiological mechanisms linked to the diagnosis of paraphilic disorders. This thesis is addressing clinical specifics and structural characteristics of the brain in sexual aggressors diagnosed with paraphilic coercive disorder. The literature review section provides an overview of theories regarding sexual arousal linked to the etiology of paraphilic coercive disorder. The empirical part of the thesis is devoted to analyzing possible structural specifics of limbic system in individuals diagnosed with paraphilic coercive disorder compared to a normophilic population of men. Volumetric brain tissue parameters in 21 individuals diagnosed with paraphilic coercive disorder and 33 controls were assessed using MRI. Following data analysis was aimed at comparing the differences in individual limbic system structures between the two aforementioned groups. No significant difference between the two groups was found in limbic system structures....

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