No (118)
Yes (1)
Used filters
(3)
Number of found documents:
119
Published from
to
Antibiotics-modes of action, resistance mechanisms and the search for new compounds
Spížek, Jaroslav
2004 - Czech
According to their mechanism of action antibiotics can be divided into 4 groups. 1. Antibiotics inhibiting bacterial cell wall biosynthesis. 2. Antibiotics inhibiting DNA synthesis. 3. Antibiotics inhibiting RNA synthesis and 4. Antibiotics inhibiting protein synthesis. Basic mechanisms of antibiotic resistance include cell impermeability, modification of target site, modification or degradation of the antibiotic and increased efflux of the antibiotic. The following can be used in the search for new compounds: 1. Microorganisms isolated from extreme life conditions 2. Environmental DNA (eDNA) in which genes coding for secondary metabolites are looked for. 3. Streptomyces genomics yielding information about genes coding biosynthesis of new compounds. 4. Combinatorial biosynthesis for the production of hybrid antibiotics. Podle mechanizmu účinku se antibiotika dělí do 4 skupin: 1. Antibiotika inhibující biosyntézu bakteriální buněčné stěny, 2. Antibiotika inhibující syntézu DNA. 3. Antibiotika inhibující syntézu RNA. 4. Antibiotika inhibující protesyntézu. Základní mechanizmy rezistence vůči antibiotikům jsou: 1. Neprůchodnost buněčných obalů. 2. Modifikace zásahového místa. 3. Modifikace nebo degradace antibiotika. 4. Zvýšený eflux antibiotika. Jako zdroj nových antibiotik mohou sloužit: 1. Mikroorganizmy izolované v extrémních podmínkách prostředí. 2. DNA izolované z prostředí (eDNA), v které jsou hledány geny kódující sekundární metabolity. 3. Genomika streptomycetů poskytující informace o genech kódujících biosyntézu nových látek. 4. Znalosti o biosyntéze sekundárních metabolitů využívané při přípravě hybridních antibiotik.
Keywords:
antibiotics; resistance
Available at various institutes of the ASCR
Antibiotics-modes of action, resistance mechanisms and the search for new compounds
According to their mechanism of action antibiotics can be divided into 4 groups. 1. Antibiotics inhibiting bacterial cell wall biosynthesis. 2. Antibiotics inhibiting DNA synthesis. 3. Antibiotics ...
Decomposition of cellulose and hemicelluloses by wood-rotting fungi and effect of heavy metals
Valášková, V.; Merhautová, Věra; Gabriel, Jiří; Baldrian, Petr
2004 - Czech
Degradation of cellulose and hemicelluloses by brown-rot fungi is significantly affected by heavy metals. The activity of cellulases is increased in the presence of zinc. Rozklad celulózy a hemicelulóz je u hub hnědé hniloby výrazně ovlivněn těžkými kovy. V přítomnosti zinku je zvýšena aktivita celulolytických enzymů.
Keywords:
piptoporus betulinus
Available at various institutes of the ASCR
Decomposition of cellulose and hemicelluloses by wood-rotting fungi and effect of heavy metals
Degradation of cellulose and hemicelluloses by brown-rot fungi is significantly affected by heavy metals. The activity of cellulases is increased in the presence of zinc.
Fomes fomentarius fruit body - a model for decompositionof cellulose in vivo
Gabriel, Jiří; Baldrian, Petr; Merhautová, Věra; Kofroňová, Olga; Král, J.; Proška, J.
2004 - Czech
Activities of both cellulolytic and ligninolytic enzymes and heavy metal content in fruit body of Fomes fomentarius were studied. The activities of ligninolytic enzymes were higher in the core. Byly měřeny aktivity ligninolytických a celulolytických enzymů v plodnici F. fomentarius. Současně byly měřeny i obsahy těžkých kovů. Zjistilo se, že nejvyšší hodnoty ligninolytických enzymů jsou v jádře.
Keywords:
aas; pixe; hplc
Available at various institutes of the ASCR
Fomes fomentarius fruit body - a model for decompositionof cellulose in vivo
Activities of both cellulolytic and ligninolytic enzymes and heavy metal content in fruit body of Fomes fomentarius were studied. The activities of ligninolytic enzymes were higher in the core.
Macromycetes in folk and oficinal medicine
Gabriel, Jiří
2004 - Czech
Review of the use of macromycetes in folk and official medicine. Přehledná práce popisující užití vyšších hub v lidové i oficinální medicíně.
Keywords:
macromycetes
Available at various institutes of the ASCR
Macromycetes in folk and oficinal medicine
Review of the use of macromycetes in folk and official medicine.
Bioavailability of PAH and its effects on biodegradation during composting
Cajthaml, Tomáš; Hubálek, Tomáš; Šašek, Václav
2004 - Czech
The publication deals with application of composting process on remediation of soils contaminated with PAHs. Bioavailability of PAHs was tested with sequential SFE and the data were compared with the results of remediation. SFE is suitable to predict results of bioremediation. Publikace se zabývá aplikací kompostovacího procesu na remediaci půd kontaminovaných PAU. Biodostupnost PAU byla sledována pomocí SFE a tyto data byly korelovány s výsledky remediace. SFE lze použít k predikci výsledků bioremediace.
Keywords:
pah; composting; biodegradation
Available at various institutes of the ASCR
Bioavailability of PAH and its effects on biodegradation during composting
The publication deals with application of composting process on remediation of soils contaminated with PAHs. Bioavailability of PAHs was tested with sequential SFE and the data were compared with the ...
Czech-Austrian cooperation in the frame of the project 2004-10
Pichová, Alena; Breitenbach, M.
2004 - Czech
Plans of Czech-Austrian cooperation on the project focused on studies of yeast cell aging in 2004-2010 are described. Jsou popsány plány česko-rakouské spolupráce na projektu studia stárnutí kvasinkových buněk na léta 2004-2010.
Keywords:
innovation
Available at various institutes of the ASCR
Czech-Austrian cooperation in the frame of the project 2004-10
Plans of Czech-Austrian cooperation on the project focused on studies of yeast cell aging in 2004-2010 are described.
Accumulationn of heavy metals by wood-rotting fungi
Gabriel, Jiří
2003 - Czech
This work summarizes data on heavy metal content in wood-rotting fungi. Their effect on the physiology of fungi is also discussed. Práce sumarizuje informace o obsazích těžkých kovů v dřevokazných houbách, popisuje mechanismy transportu. Též je diskutován vliv kovů na fysiologii hub.
Keywords:
wood-inhabiting; atmospheric
Available at various institutes of the ASCR
Accumulationn of heavy metals by wood-rotting fungi
This work summarizes data on heavy metal content in wood-rotting fungi. Their effect on the physiology of fungi is also discussed.
Characterization of tumor specific lymphocytes after devitalization of minipig melanoma
Šinkora, Jiří; Horák, Vratislav; Řeháková, Zuzana; Hradecký, Jan; Málek, Ondřej; Klaudy, Jiří
2003 - Czech
Distribution of leukocytes among growing minipig melanoma and their characterization were studied. Linie miniaturních prasat označená akronymem byla získána v Lichnově několikaletou selekcí a částečnou inbredizací jako nový zvířecí modelpro studium maligního melanomu.
Keywords:
tumor; lymphocytes
Available at various institutes of the ASCR
Characterization of tumor specific lymphocytes after devitalization of minipig melanoma
Distribution of leukocytes among growing minipig melanoma and their characterization were studied.
Accumulation of metals in fruiting bodies of Fomes fomentarius
Gabriel, Jiří; Baldrian, Petr; Kofroňová, Olga; Benada, Oldřich
2003 - Czech
Fruit body of Fomes fomentarius was used for detailed study of metal distribution within fungus and wood. Higher content of Mn was found in the core. Plodnice Fomes fomentarius byla použita k detailní studii distribuce kovů v houbách. Několikanásobně vyšší koncentrace Mn byly nalezeny v jádře, ve srovnání s ostatními částmi houby či dřeva.
Keywords:
hymenium; trama contained
Available at various institutes of the ASCR
Accumulation of metals in fruiting bodies of Fomes fomentarius
Fruit body of Fomes fomentarius was used for detailed study of metal distribution within fungus and wood. Higher content of Mn was found in the core.
16S rRNA fish and FCM of intestinal bycteria
Šinkora, J.; Řeháková, Zuzana
2003 - Czech
16S-rRNA-FISH-FCM analysis was used to confirm genetical analysis of bacteria isolated from experimental models. 16 S-rRNA-FISH-FCM analysis was used to confirm genetical analysis of bacteria isolated from experimental models.
Keywords:
fish; fcm; RNA; analýza
Available at various institutes of the ASCR
16S rRNA fish and FCM of intestinal bycteria
16S-rRNA-FISH-FCM analysis was used to confirm genetical analysis of bacteria isolated from experimental models.
NRGL provides central access to information on grey literature produced in the Czech Republic in the fields of science, research and education. You can find more information about grey literature and NRGL at service web
Send your suggestions and comments to nusl@techlib.cz
Provider
Other bases