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Number of found documents:
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Adaptation of methods for cyclo-stationary processes for noisy structural health data
Fischer, Cyril; Bayer, Jan; Náprstek, Jiří; Urushadze, Shota
2023 - English
In structural health analysis, various techniques, including indirect measurement via monitoring vehicles, often yield data with significant randomness and insufficient frequency separation. Conversely, the desired attributes under scrutiny are periodic in nature. Thus, methodologies designed to identify cyclo-stationary properties within noisy data can be adapted for such scenarios, assuming an adequate length of the recorded data.
Keywords:
data analysis; cyclo-stationary processes; structural health monitoring
Available at various institutes of the ASCR
Adaptation of methods for cyclo-stationary processes for noisy structural health data
In structural health analysis, various techniques, including indirect measurement via monitoring vehicles, often yield data with significant randomness and insufficient frequency separation. ...
Consistency of mathematical and experimental model of the autoparametric system
Fischer, Cyril; Náprstek, Jiří
2023 - English
This paper presents a long-overdue comparison of data obtained from experimental investigation of a spherical vibration absorber with the results of two mathematical models of the motion of a heavy sphere in a spherical surface. It shows that the danger posed by the potentially unstable self-parametric nature of the mathematical system is not too great in the case of realistic configurations, and that the values of the parameters describing the realistic structures remain within intervals corresponding to the stable behaviour of the absorber.
Keywords:
vibration absorber; rolling sphere; spherical surface; autoparametric system; structural health monitoring
Available at various institutes of the ASCR
Consistency of mathematical and experimental model of the autoparametric system
This paper presents a long-overdue comparison of data obtained from experimental investigation of a spherical vibration absorber with the results of two mathematical models of the motion of a heavy ...
Biopharmaceuticals from the MS point of view
Hubálek, Martin; Lenčo, J.
2023 - Czech
The course aims to introduce biotherapeutics, which are becoming an increasingly important part of the pharmacotherapy of serious diseases. Mass spectrometry plays an important role for their quality control in the pharmaceutical industry. We will introduce the audience to biopharmaceuticals, which in this context are peptides, proteins, monoclonal antibodies or oligonucleotides. From the analyst's point of view, we will focus mainly on antibody drugs, looking at the possibilities of their separation and analysis by mass spectrometry, at the level of intact protein molecules, antibody subunits or peptides. Kurz má za cíl představit bioléčiva, která se stávají stále významnější součástí farmakoterapie závažných onemocnění. Pro kontrolu jejich kvality ve farmaceutickém průmyslu hraje důležitou roli hmotnostní spektrometrie. Uvedeme posluchače do problematiky bioléčiv, kterými jsou v tomto pohledu peptidy, proteiny, monoklonální protilátky nebo oligonukleotidy. Z pohledu analytika se zaměříme především na protilátková léčiva, podíváme se na možnosti jejich separace a analýzy pomocí hmotnostní spektrometrie, a to na úrovni intaktních proteinových molekul, protilátkových podjednotek nebo peptidů.
Keywords:
mass spectrometry; biopharmaceuticals; LC-MS
Available on request at various institutes of the ASCR
Biopharmaceuticals from the MS point of view
The course aims to introduce biotherapeutics, which are becoming an increasingly important part of the pharmacotherapy of serious diseases. Mass spectrometry plays an important role for their quality ...
On Semantic Transformation of one term “výtečník”
Velek, Luboš
2023 - Czech
The study analyses the emergence of the term “výtečník” and its transformations in Czech politics and culture in the 19th and 20th centuries. Studie analyzuje vznik termínu „výtečník“ a jeho významové proměny v české politice a kultuře 19. a 20. století.
Keywords:
political culture; Bohemia, patriotic society; Habsburg monarchy
Available at various institutes of the ASCR
On Semantic Transformation of one term “výtečník”
The study analyses the emergence of the term “výtečník” and its transformations in Czech politics and culture in the 19th and 20th centuries.
Research contacts between Bohemia and Moravia. Contribution to the mutual cooperation of Innocenc Ladislav Červinka and Kliment Čermák
Velímský, Filip
2023 - Czech
Kliment Čermák, the archaeologist and museum curator in Čáslav, established and during his lifetime maintained relatively abundant contacts with a number of personalities from the Moravian archaeological community. The contribution provides a partial overview of these contacts with individual researchers, especially with Innocenc Ladislav Červinka, while is primarily based on the preserved correspondence and manuscripts stored as part of Čermák's estate in the Literary Archive of the Museum of Czech Literature in Prague, the Archive of the Municipal Museum and Library in Čáslav and the State District Archive in Kutná Hora. The contribution also includes the information about the mutual publication of texts on the pages of the periodicals of the Museum and Patriotic Society „Včela Čáslavská“, the Patriotic Museum Society in Olomouc and the Moravian Archaeological Club. Čáslavský archeolog a muzejník Kliment Čermák navázal a po dobu svého života pak i udržoval poměrně hojné styky s řadou osobností z moravské archeologické obce. Příspěvek přináší dílčí přehled těchto kontaktů s jednotlivými badateli, zejména pak Innocencem Ladislavem Červinkou, přičemž primárně vychází z dochované korespondence a rukopisů uložených v rámci Čermákovy pozůstalosti v Literárním archivu Památníku národního písemnictví v Praze, Archivu Městského muzea a knihovny v Čáslavi a Státního okresního archivu v Kutné Hoře. Do příspěvku jsou zahrnuty i zjištěné informace o vzájemném publikování textů na stránkách spolkových periodik Muzejního a vlastivědného spolku „Včela Čáslavská“, Vlasteneckého spolku muzejního v Olomouci a Moravského archeologického klubu.
Keywords:
Kliment Čermák; Innocenc Ladislav Červinka; archaeology; collaboration between researchers; correspondence
Available at various institutes of the ASCR
Research contacts between Bohemia and Moravia. Contribution to the mutual cooperation of Innocenc Ladislav Červinka and Kliment Čermák
Kliment Čermák, the archaeologist and museum curator in Čáslav, established and during his lifetime maintained relatively abundant contacts with a number of personalities from the Moravian ...
How to speak in the Czech Republic or what we know about dialects of Czech
Ireinová, Martina; Konečná, Hana
2023 - Czech
The lecture deals with different dialects of different speeches in Moravia and Silesia. Přednáška se zabývá rozdílnými dialekty různé mluvy na Moravě a ve Slezsku.
Keywords:
Czech language; dilects; Moravia; Silesia; Czech Linguistic Atlas
Available at various institutes of the ASCR
How to speak in the Czech Republic or what we know about dialects of Czech
The lecture deals with different dialects of different speeches in Moravia and Silesia.
Hidden cultural values of the protected areas
Fišer, J.; Novák, David; Šmejda, L.
2023 - Czech
The cultural character of the landscape stems not only from its current economic structure but also from the anthropogenic past reflected in numerous relics, which show that people in the past also used the part of the landscape that is now protected for its natural values. However, the intensity of these activities was linked to general settlement strategies with a strong respect to the geomorphological characteristics of the landscape. Large-scale protected natural areas are characterised by exceptional landscape features or significant natural values. Even in these parts of the landscape, past human influence was significant and left its traces. The intensity and specifics of this influence are presented in the paper on the basis of archaeological data. The archaeological data were processed into a grid whose values are related to the number of archaeological periods present in the given area. The protected landscape was used by people rather sporadically and the increase in activity can only be associated with the mediaeval and modern periods. Areas of the unprotected landscape were more intensively used in the past. However, the explanation for the difference is not based on social preferences but on the geomorphological structure of the protected landscape and its associated settlement history. Kulturní charakter krajiny vyplývá nejen z její současné hospodářské struktury, ale také z antropogenní minulosti, která se odráží v četných památkách, jež ukazují, že lidé v minulosti využívali i tu část krajiny, která je nyní chráněna pro své přírodní hodnoty. Intenzita těchto činností však byla spojena s obecnými strategiemi osídlení, které výrazně respektovaly geomorfologické charakteristiky krajiny. Velkoplošná chráněná přírodní území se vyznačují výjimečnými krajinnými prvky nebo významnými přírodními hodnotami. I v těchto částech krajiny byl minulý vliv člověka významný a zanechal zde své stopy. Intenzita a specifika tohoto vlivu jsou v článku prezentovány na základě archeologických dat. Archeologická data byla zpracována do rastru, jehož hodnoty jsou vztaženy k počtu archeologických období přítomných v daném území. Chráněná krajina byla lidmi využívána spíše sporadicky a nárůst aktivity lze spojit až s obdobím středověku a novověku. Plochy nechráněné krajiny byly v minulosti využívány intenzivněji. Vysvětlení tohoto rozdílu však není založeno na sociálních preferencích, ale na geomorfologické struktuře chráněné krajiny a s ní spojené historii osídlení.
Keywords:
past human activities; archaeology; protected natural sites; landscape history; land use
Available at various institutes of the ASCR
Hidden cultural values of the protected areas
The cultural character of the landscape stems not only from its current economic structure but also from the anthropogenic past reflected in numerous relics, which show that people in the past also ...
Laser ablation of calcium and aluminium atoms as a particle source for ion trap
Grim, Jakub; Pekař, Zdeněk; Pham, Minh Tuan; Číp, Ondřej
2023 - Czech
Laser ablation is an effective method for generating particles from a variety of materials, including those with high evaporation temperatures such as aluminum. The use of high-energy laser pulses enables controlled evaporation of the material and the creation of an ablation crater. Successful results have been obtained in a pilot setup for the generation of neutral calcium and aluminium atoms by laser ablation. The method is being compared with thermal resistance oven in order to optimize the prosec generation of these particles. Subsequent spectroscopic measurements on the generated atoms are performed to optimize the absorption and emission of photons for subsequent ionization in the ion trap. A study of the transitions of neutral Ca and Al atoms shows that laser ablation provides a more efficient generation of atoms with the possibility of greater control over the process. Laserová ablace je účinnou metodou pro generování částic z různých materiálů, včetně těch s vysokou teplotou vypařování, jako je hliník. Využití vysokoenergetických laserových pulsů umožňuje kontrolované odpaření materiálu a vytvoření ablačního kráteru. V pilotní sestavě pro generování neutrálních atomů vápníku a hliníku pomocí laserové ablace byly dosaženy úspěšné výsledky. Metoda je porovnávána s tepelnou píckou s cílem optimalizovat proces generování těchto částic. Následná spektroskopická měření na generovaných atomech jsou prováděna s cílem optimalizace absorpce a emise fotonů pro následnou ionizaci v iontové pasti. Studie přechodů neutrálních atomů Ca a Al ukazuje, že laserová ablace poskytuje efektivnější generaci atomů s možností větší kontroly nad tímto procesem.
Keywords:
laser ablation; ion trap; particle generation; fluorescence spectroscopy
Available at various institutes of the ASCR
Laser ablation of calcium and aluminium atoms as a particle source for ion trap
Laser ablation is an effective method for generating particles from a variety of materials, including those with high evaporation temperatures such as aluminum. The use of high-energy laser pulses ...
Comparison of finite element simulation of tungsten nanoindentation with Berkovich and conical indenter
Fiala, L.; Ballo, I.; Kovář, J.; Fuis, Vladimír
2023 - English
Finite Element Method (FEM) was used to study the difference between using Berkovich and conical indenters in nanoindentation test of tungsten specimen. The study was aimed to determine the\nmodulus of elasticity of a tested specimen and how it changes with different indenter. The FEM analysis also revealed that the modulus of elasticity was sensitive to the dimensions of both specimen and the indenter for which were made several numerical calculations with different dimensions.
Keywords:
nanoindentation; FEM; Berkovich indenter; conical indenter; tungsten
Available at various institutes of the ASCR
Comparison of finite element simulation of tungsten nanoindentation with Berkovich and conical indenter
Finite Element Method (FEM) was used to study the difference between using Berkovich and conical indenters in nanoindentation test of tungsten specimen. The study was aimed to determine the\nmodulus ...
Analysis of secondary metabolites from Streptomyces by Raman spectroscopy in vivo
Mikulová, Adéla; Petříčková, K.; Bobek, J.; Chroňáková, Alica; Samek, Ota; Pilát, Zdeněk
2023 - Czech
The work deals with the study of Raman spectra of secondary metabolites of bacteria of the genus Streptomyces, especially polyene antifungal agents. Purified isolates and commercial standards of these compounds were used to obtain reference spectra from which spectral markers characterizing specific details of the chemical structure were derived. Verification of the observed markers was performed using in silico Raman spectra predictions. Subsequently, these findings were used for the spectroscopic characterization of the composition of secondary metabolites in vivo, directly in bacteria growing on a solid medium. The developed methodologies will help to optimize the conditions for the biotechnological production of antibiotics. Práce se zabývá studiem Ramanových spekter sekundárních metabolitů bakterií rodu Streptomyces, zejména polyenních antifungálních látek. Purifikované izoláty a komerční standardy těchto sloučenin byly využity k pořízení referenčních spekter, ze kterých byly odvozeny spektrální markery charakterizující konkrétní detaily chemické struktury. Verifikace pozorovaných markerů byla provedena pomocí predikcí Ramanových spekter in silico. Následně byly tyto poznatky využity ke spektroskopické charakterizaci složení sekundárních metabolitů in vivo, přímo v bakteriích rostoucích na pevném médiu. Vypracované metodiky pomohou optimalizovat podmínky pro biotechnologickou produkci antibiotik.
Keywords:
Raman spectroscopy; microbiology; Streptomyces; antibiotics
Available at various institutes of the ASCR
Analysis of secondary metabolites from Streptomyces by Raman spectroscopy in vivo
The work deals with the study of Raman spectra of secondary metabolites of bacteria of the genus Streptomyces, especially polyene antifungal agents. Purified isolates and commercial standards of these ...
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