Number of found documents: 124
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Nanotechnologies in regenerative medicine
Syková, Eva
2010 - English
Magnetic resonance imaging provides a noninvase method to study the fate of transplanted cells in vivo. Various biocomatible scaffolds based on non-woven nanofibres (products of ELMARCO or Technical University Liberec), have been developed for bridging tissue defects and for use as 3D stem cell careiers. Keywords: ELMARCO; magnetic resonance; stem cells; magnetická rezonance Available at various institutes of the ASCR
Nanotechnologies in regenerative medicine

Magnetic resonance imaging provides a noninvase method to study the fate of transplanted cells in vivo. Various biocomatible scaffolds based on non-woven nanofibres (products of ELMARCO or Technical ...

Syková, Eva
Ústav experimentální medicíny, 2010

Modeling of nucleolar self-assembly
Blažíková, Michaela; Heřman, P.; Malínský, Jan
2010 - English
Mammalian cell nucleoli disassemble at the beginning of mitosis and reassemble again during telophase and the early G1. Dynamics of this process was studied using a model based on entropy driven self-assembly of pre-ribosomal particles generated in a single biosynthetic source. Monte Carlo simulations revealed that such model can explain formation of a large aggregate, a nucleolus, in the vicinity of the source. We examined influence of nucleoplasm properties on dynamics of the aggregate formation. Keywords: Monte Carlo simulations; dynamika; montáž Available at various institutes of the ASCR
Modeling of nucleolar self-assembly

Mammalian cell nucleoli disassemble at the beginning of mitosis and reassemble again during telophase and the early G1. Dynamics of this process was studied using a model based on entropy driven ...

Blažíková, Michaela; Heřman, P.; Malínský, Jan
Ústav experimentální medicíny, 2010

NANOTECHNOLOGY AND BIOMATERIALS IN MEDICINE
Kubinová, Šárka; Jendelová, Pavla; Lesný, Petr; Holáň, Vladimír; Syková, Eva
2009 - English
Our studies focus on the use of nanotechnology in cell therapy and tissue engineering for the treatment of brain and spinal cord injury, corneal defects and chronic wounds. Keywords: superparamagnetic iron oxide; mesenchymal stem cells; embryonic stem cells; kmenové buňky; buňky Available at various institutes of the ASCR
NANOTECHNOLOGY AND BIOMATERIALS IN MEDICINE

Our studies focus on the use of nanotechnology in cell therapy and tissue engineering for the treatment of brain and spinal cord injury, corneal defects and chronic wounds.

Kubinová, Šárka; Jendelová, Pavla; Lesný, Petr; Holáň, Vladimír; Syková, Eva
Ústav experimentální medicíny, 2009

Role of glial cells in extrasynaptic communication
Syková, Eva
2003 - English
It is evident that during neuronal activity and pathological states, the movement of substances in the brain is not only hindered by the size of the pores between the cells, but also by the structure of the glial cells. These changes, together with K+ and pH changes in the ECS, affect the efficacy of interneuronal and neurone-glia communication. Keywords: Glial cells; extrasynaptic communication Available at various institutes of the ASCR
Role of glial cells in extrasynaptic communication

It is evident that during neuronal activity and pathological states, the movement of substances in the brain is not only hindered by the size of the pores between the cells, but also by the structure ...

Syková, Eva
Ústav experimentální medicíny, 2003

Human embryonic stem cell line originating from blastocyst produced by intracytoplasmic sperm injection
Hampl, Aleš; Jendelová, Pavla; Syková, Eva; Dvořák, Petr
2003 - English
The biological properties of the AL1 ES cell line will be assessed by introducing the cells into the brains of adult Wistar rats following a unilateral cortical photochemical lesion. Keywords: Human embryonic stem cell Available at various institutes of the ASCR
Human embryonic stem cell line originating from blastocyst produced by intracytoplasmic sperm injection

The biological properties of the AL1 ES cell line will be assessed by introducing the cells into the brains of adult Wistar rats following a unilateral cortical photochemical lesion.

Hampl, Aleš; Jendelová, Pavla; Syková, Eva; Dvořák, Petr
Ústav experimentální medicíny, 2003

Detekce molekulárních znaků embryonálních kmenových buněk
Dvořák, Petr; Bryja, Vítězslav; Pacherník, Jiří; Hampl, Aleš
2003 - Czech
Keywords: stem cell Available at various institutes of the ASCR
Detekce molekulárních znaků embryonálních kmenových buněk

Dvořák, Petr; Bryja, Vítězslav; Pacherník, Jiří; Hampl, Aleš
Ústav experimentální medicíny, 2003

Lewis X, developmentally regulated carbohydrate is abundantly expressed in embryonic and adult neural stem cells and regulates their self-renewal and/or differentiation
Dvořák, Petr; Hampl, Aleš
2003 - English
Keywords: neural stem cell Available at various institutes of the ASCR
Lewis X, developmentally regulated carbohydrate is abundantly expressed in embryonic and adult neural stem cells and regulates their self-renewal and/or differentiation

Dvořák, Petr; Hampl, Aleš
Ústav experimentální medicíny, 2003

Stem cells and therapy of brain and spinal cord injury
Syková, Eva; Jendelová, Pavla; Glogarová, Kateřina; Urdzíková, Lucia; Lesný, Petr; Hampl, Aleš; Dvořák, Petr
2003 - English
Our studies demonstrate the potential of SC as a therapeutic tool in the treatment of injury and degenerative diseases, explain the effects of certain drugs on neurogenesis and regeneration and show that there may be various ways in which SC may interact with the host CNS tissue. Keywords: stem cells; kmenové buňky Available at various institutes of the ASCR
Stem cells and therapy of brain and spinal cord injury

Our studies demonstrate the potential of SC as a therapeutic tool in the treatment of injury and degenerative diseases, explain the effects of certain drugs on neurogenesis and regeneration and show ...

Syková, Eva; Jendelová, Pavla; Glogarová, Kateřina; Urdzíková, Lucia; Lesný, Petr; Hampl, Aleš; Dvořák, Petr
Ústav experimentální medicíny, 2003

Diffusion properties of the brain in health and disease
Syková, Eva
2003 - English
Diffusion parameters affect neurone-glia communication, ionic homeostasis, the movement and accumulation of neuroactive substances and, therefore, play an important role in synaptic as well as volume transmission. Keywords: Diffusion properties; brain; mozek Available at various institutes of the ASCR
Diffusion properties of the brain in health and disease

Diffusion parameters affect neurone-glia communication, ionic homeostasis, the movement and accumulation of neuroactive substances and, therefore, play an important role in synaptic as well as volume ...

Syková, Eva
Ústav experimentální medicíny, 2003

Implantation of bone marrow stromal cells labeled with superparamagnetic nanoparticles into injured brain and imaging their fate by magnetic resonance
Jendelová, Pavla; Herynek, V.; Glogarová, Kateřina; Hájek, M.; Syková, Eva
2003 - English
Our study demonstrates that MSCs only migrate into an injured brain region. The commercially available contrast agent Endorem can be used as a cell marker for noninvasive MR tracking of implanted stem cells. Keywords: bone marrow stromal cells; nanoparticles Available at various institutes of the ASCR
Implantation of bone marrow stromal cells labeled with superparamagnetic nanoparticles into injured brain and imaging their fate by magnetic resonance

Our study demonstrates that MSCs only migrate into an injured brain region. The commercially available contrast agent Endorem can be used as a cell marker for noninvasive MR tracking of implanted stem ...

Jendelová, Pavla; Herynek, V.; Glogarová, Kateřina; Hájek, M.; Syková, Eva
Ústav experimentální medicíny, 2003

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